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2006
Structure-function
mapping of BbCRASP-1, the key complement factor H
and FHL-1 binding protein of Borrelia
burgdorferi
Cordes, F.S. et al., IJMM, in
the press
Expression, purification, crystallisation
and preliminary crystallographic analsysis of MxiH, as subunit of the Shigella flexneri type III
secretion system needle
Deane, J.E. et al., Acta
Cryst. F62, 302-305
The
interaction of echoviruses and decay accelerating factor (DAF):
Structural and functional insights
Pettigrew, D.P. et al., J.
Biol. Chem., 281, 5169-5177
The characterization of weak
protein-protein interactions: Evidence from DEER for the trimerization
of a von Willebrand factor A domain in solution.
Banham, J.E. et al., Angew.
Chem. Int. Ed., 45, 1058-1061
2005
The type III
needle and the damage done
Johnson, S., Deane, J & Lea, S.M., Curr. Op. Struct. Biol., 15, 700-707
Helical
packing of needles from functionally altered Shigella type III secretion systems
Cordes, F.S. et al., J. Mol.
Biol., 354, 206-211
An
aptamer that neutralises R5 strains of human immunodeficiency virus
type 1 blocks gp120-CCR5 interaction
Dey, A.K. et al., J. Virol., 79, 13806-138210
Structure
of Foot-and-mouth disease virus serotype A1061 alone and
complexed with oligosaccharide receptor: receptor conservation in the
face of antigenic variation
Fry, E. et al., J. Gen.
Virol., 86, 1909-1920
Hydrophillic
domain II of E. coli Dr
fimbrae facilitates cell invasion
Das, M. et al., Infection
& Immunity, 73, 6119-6126
Structural
characterisation of an anti-gp120 aptamer that neutralizes R5 strains
of HIV-1
Dey, A.K. et al., RNA, 11, 873-884
A novel fold for BbCRASP-1, a key
complement factor H-binding outer surface protein of Borrelia burgdorferi
Cordes, F.S. & Roversi, P. et al., Nat.
Struct. Molec. Biol., 12, 276-277 [PDB IDs: 1w33,
1w3z
]
Molecular dissection of interactions between components
of the alternative pathway of complement and decay accelerating factor
(CD55)
Harris, C.L. et al., J.Biol.Chem., 280, 2569-2578
From structure to
function
of a complement regulator: Decay accelerating factor (CD55)
Lukacik, P. et al., in
Structural
Biology
of the Complement System, ed Lambris
2004
High resolution studies of the Afa/Dr adhesin DraE and
its interaction with
chloramphenicol
Pettigrew, D. & Anderson, K.
et al., J.Biol.Chem., 279,
46851-46857 [PDB IDs:
1ut1
, 1ut2
, 1usq
, 1usz
]
An atomic resolution model for assembly, architecture,
and function of the
Dr adhesins.
Anderson, K. & Billington, J. et al., Molecular Cell,
15, 647-657
Biological activity, membrane-targeting modification and
crystallisation
of soluble human decay accelerating factor expressed in E.coli.
White,
J. et al. , Protein Science,
13, 2406-2415
Refinement
of severely incomplete structures with maximum likelihood in
Buster-TNT.
Blanc,
E & Roversi, P. et al.,
Acta Cryst, D60, 2210-2221
Crystallisation and preliminary X-ray diffraction
analysis of three EGF domains of EMR2, a 7-TM immune system molecule.
Abbott,
R.J.M. et al., Acta Cryst,
D60,
936-938
Crystallisation and preliminary crystallographic analysis
of BbCRASP-1, a complement regulator-acquiring surface protein of Borrelia burgdorferi
Cordes,
F.S. et al., Acta Cryst, D60,
929-932
Complement
regulation at the molecular level: the structure of Decay Accelerating
Factor.
Lukacik, P. et al.,
Proc.
Natl. Acad. Sci. USA, 105(5), 1279-1284 (2004).
[PDB IDs: 1ojv
, 1ojw
, 1ojy
, 1ok2
, 1ok3
, 1ok1
, 1ok9
]
Interaction
of Decay Accelerating Factor (DAF) with hemagglutinating human
enteroviruses: Utilising variation in primate DAF to map virus binding
sites.
Williams, D. et al.,
J.
Gen.
Virol., 85(3), 731-738
The
structure of echovirus type 12 bound to a two-domain fragment of its
cellular
attachment protein decay accelerating factor (CD55).
Bhella, D. et al.,
J.
Biol.
Chem. 2004 Feb 27;279(9):8325-8332. [PDB ID:
1upn
]
2003
Model
of the equine rhinitis A virus capsid: identification of a major
neutralizing
immunogenic site.
Kriegshauser et al.
,
J Gen Virol. 2003 Sep;84(Pt 9):2365-2373.
Rev
binds
specifically to a purine loop in the SL1 region of the HIV-1 leader RNA.
Gallego et al., J
Biol
Chem. 2003 Oct 10;278(41): 40385-91.
Helical
structure of the needle of the type III secretion system of Shigella flexneri.
Cordes, F.S. et al.,
J
Biol
Chem. 2003 May 9;278(19):17103-7
Mapping
CD55 function. The structure of two pathogen-binding domains at 1.7 A.
Williams, P.A. et al.,
J
Biol
Chem. 2003 Mar 21;278(12):10691-6. [PDB IDs:
1h04
, 1h03
, 1h2p
, 1h2q
, 1uot
]
2002
Interactions
of CD55 with non-complement ligands.
Lea, S., Biochem Soc Trans. 2002 Nov;30(Pt 6):1014-9.
Determination
of the structure of a decay accelerating factor-binding clinical
isolate
of echovirus 11 allows mapping of mutants with altered receptor
requirements
for infection.
Stuart, A. et al.,
J
Virol.
2002 Aug;76(15):7694-704. [PDB ID:
1h8t
]
2001
Molecular
analysis
of the epidermal growth factor-like short consensus repeat
domain-mediated protein-protein interactions: dissection of the
CD97-CD55 complex.
Lin, H.-S. et al., J Biol
Chem.
2001 Jun 29;276(26):24160-9
1999
Crystallization
and preliminary X-ray diffraction analysis of a biologically active
fragment of CD55.
Lea et al., Acta
Crystallogr
D Biol Crystallogr. 1999 Jun;55 ( Pt 6):1198-200.
The
structure and function of a foot-and-mouth disease
virus-oligosaccharide
receptor complex.
Fry et al., EMBO J.
1999
Feb 1;18(3):543-54.
1998
Determination
of the affinity and kinetic constants for the interaction between the
human
virus echovirus 11 and its cellular receptor, CD55.
Lea et al., J Biol
Chem.
1998 Nov 13;273(46):30443-7.
Characterizing sequence variation in the VP1 capsid proteins
of
foot and mouth disease virus (serotype 0) with respect to virion
structure.
Haydon et al., J
Mol Evol. 1998 Apr;46(4):465-75.
1997
Dissecting
the roles of VP0 cleavage and RNA packaging in picornavirus capsid
stabilization:
the structure of empty capsids of foot-and-mouth disease virus.
Curry et al., J
Virol.
1997 Dec;71(12):9743-52.
1996
Perturbations in the surface structure of A22 Iraq
foot-and-mouth disease virus accompanying coupled changes in host cell
specificity and antigenicity.
Curry et al.,
Structure.
1996 Feb 15;4(2):135-45.
1995
Structural comparison of two strains of
foot-and-mouth disease virus subtype O1 and a laboratory antigenic
variant, G67.
Lea et al.,
Structure.
1995 Jun 15;3(6):571-80.
Deconvolution of fully overlapped reflections from
crystals of foot-and-mouth-disease virus O-1 G67
Lea
S and Stuart D, Acta Crystallogr D Biol Crystallogr 1995; 51 (Pt 2):
160-167
Analysis of antigenic surfaces of proteins.
Lea S and Stuart D, FASEB J. 1995 Jan;9(1):87-93.
1994
Antigenic heterogeneity of a foot-and-mouth disease
virus serotype in the field is mediated by very limited sequence
variation at several antigenic sites.
Mateu et al., J
Virol.
1994 Mar;68(3):1407-17.
The structure and antigenicity of a type C foot-and-mouth
disease
virus.
Lea et al.,
Structure.
1994 Feb 15;2(2):123-39.
The structure of an immunodominant loop on foot and mouth
disease
virus, serotype O1, determined under reducing conditions.
Rowlands et al.,
Arch
Virol Suppl. 1994;9:51-8.
1993
Structure of a major immunogenic site on
foot-and-mouth disease virus.
Logan et al.,
Nature.
1993 Apr 8;362(6420):566-8.
1992
Crystallization and preliminary X-ray analysis of
three serotypes of foot-and-mouth disease virus.
Curry et al., J Mol
Biol.
1992 Dec 20;228(4):1263-8.
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