An alignment of 11 sequences of part of an enzyme called Urease. Urease allows a bacterium called Helicobacter pylori to damage the lining of the stomach causing ulcers. The alignment shows positions, shaded black, where the same amino acid is seen in all of the sequences. Positions where similar amino acids are seen are shaded grey. Positions containing different amino acids are not shaded and the letter representing the amino acid is shown in small (unreadable!) type. The graphs below show the degree to which a computer program judges a position to be likely to be part of a helix, strand or loop region of the protein. The coloured rectangles show the decisions made by a person based on the judgement of the program and their examination of the sequences. Red rectangles show predictions of helix and green ones are predicted strand regions.